Author: Janet S. Butel (PhD)
427 Elements
|
LogUser ID Element ID |
Node Node Type |
Content |
Status Date |
|
|---|---|---|---|---|
|
120971 87565 |
genus_genome_gc text |
47.3 |
approved 2021-04-19 18:26 |
Open genus containing this element |
|
120970 87566 |
genus_genome_mrna text |
7 |
approved 2021-04-19 18:26 |
Open genus containing this element |
|
120969 87567 |
genus_genome_info text |
Genome is nonsegmented, closed circular, supercoiled; viral minichromosome within virions is complexed with histones H2A, H2B, H3, and H4, but lacks H1 |
approved 2021-04-19 18:26 |
Open genus containing this element |
|
120968 87568 |
genus_replication_entry text |
Caveolae- or clathrin-mediated endocytosis |
approved 2021-04-19 18:26 |
Open genus containing this element |
|
120967 87569 |
genus_replication_tsite text |
Nucleus |
approved 2021-04-19 18:26 |
Open genus containing this element |
|
120966 87570 |
genus_replication_tase text |
Host cell RNA polymerase II and its accessory proteins |
approved 2021-04-19 18:26 |
Open genus containing this element |
|
120965 87571 |
genus_replication_rsite text |
Nucleus |
approved 2021-04-19 18:26 |
Open genus containing this element |
|
120964 87572 |
genus_replication_rase text |
SV40 large tumor antigen, DNA pol alpha-primase, DNA pol delta/RFC/PCNA |
approved 2021-04-19 18:26 |
Open genus containing this element |
|
120963 87573 |
genus_replication_rint text |
Unknown |
approved 2021-04-19 18:26 |
Open genus containing this element |
|
120962 87574 |
genus_replication_asite text |
Nucleus |
approved 2021-04-19 18:25 |
Open genus containing this element |
|
120961 87575 |
genus_replication_egress text |
Virus release occurs by cytolysis; cytoplasmic vesicles also transport some virions to cell surface |
approved 2021-04-19 18:25 |
Open genus containing this element |
|
120960 87576 |
genus_replication_info text |
Ganglioside GM1 is cell-surface receptor for SV40; MHC class I proteins may be co-receptors. Virions taken up in caveosomes, transported to smooth ER, enter nucleus via nuclear pore by recognition of nuclear localization signal in viral protein VP3 |
approved 2021-04-19 18:25 |
Open genus containing this element |
|
120959 87577 |
genus_history text |
Detection of simian vacuolating agent 40 (SV40) as a contaminant of poliovaccines |
approved 2021-04-19 18:25 |
Open genus containing this element |
|
120958 87578 |
genus_history_year text |
1960 |
approved 2021-04-19 18:25 |
Open genus containing this element |
|
120957 87579 |
genus_history_ref text |
Sweet BH, Hilleman MR (1960) Proc Soc Exp Biol Med 105:420-427 |
approved 2021-04-19 18:25 |
Open genus containing this element |
|
120956 87580 |
genus_history text |
Discovery that SV40 is oncogenic in hamsters |
approved 2021-04-19 18:25 |
Open genus containing this element |
|
120955 87581 |
genus_history_year text |
1962 |
approved 2021-04-19 18:25 |
Open genus containing this element |
|
120954 87582 |
genus_history_ref text |
Eddy BE et al (1962) Virology 17:65-75; Girardi AJ et al (1962) Proc Soc Exp Biol Med 109:649-660 |
approved 2021-04-19 18:25 |
Open genus containing this element |
|
120953 87583 |
genus_history text |
SV40 plaque assay |
approved 2021-04-19 18:25 |
Open genus containing this element |
|
120952 87584 |
genus_history_year text |
1962 |
approved 2021-04-19 18:25 |
Open genus containing this element |